Alexander N. Comninos, Matthew B. Wall, Lysia Demetriou, Amar J. Shah, Sophie A. Clarke, Shakunthala Narayanaswamy, Alexander Nesbitt, Chioma Izzi-Engbeaya, Julia K. Prague, Ali Abbara, Risheka Ratnasabapathy, Victoria Salem, Gurjinder M. Nijher, Channa N. Jayasena, Mark Tanner, Paul Bassett, Amrish Mehta, Eugenii A. Rabiner, Christoph Hönigsperger, Meire Ribeiro Silva, Ole Kristian Brandtzaeg, Elsa Lundanes, Steven Ray Wilson, Rachel C. Brown, Sarah A. Thomas, Stephen R. Bloom, Waljit S. Dhillo
Experimental protocol and effects of kisspeptin administration on hormone levels.
Twenty-nine healthy young men participated in a randomized, double-blinded, 2-way crossover, placebo-controlled study. They participated in 2 study visits: one for intravenous administration of kisspeptin (1 nmol/kg/h) and one for intravenous administration of an equivalent volume of vehicle for 75 minutes. Participants completed baseline and intrainfusion questionnaires (Q) and underwent functional MRI scanning while performing image tasks (see Methods). (