Chlamydia pneumoniae multiplies in human endothelial cells in vitro

SS Kaukoranta-Tolvanen, K Laitinen, P Saikku… - Microbial …, 1994 - Elsevier
The ability of three C. pneumoniae isolates, Kajaani 6, Helsinki 12 and TW-183, to grow in
human umbilical vein endothelial cells (HUVEC) and in an immortalized endothelial cell line
EA. hy 926 was studied. All C. pneumoniae isolates were capable of multiplying in
endothelial cells. EA. hy 926 cells could support the growth of C. pneumoniae better than
HUVEC, yet less efficiently than HL and HEp-2 cells that are conventionally used in C.
pneumoniae culturing. Although centrifugation of the inoculum greatly increased the …