Human corneal basement membrane heterogeneity: topographical differences in the expression of type IV collagen and laminin isoforms.
AV Ljubimov, RE Burgeson, RJ Butkowski… - … ; a journal of technical …, 1995 - europepmc.org
AV Ljubimov, RE Burgeson, RJ Butkowski, AF Michael, TT Sun, MC Kenney
Laboratory investigation; a journal of technical methods and pathology, 1995•europepmc.orgBackground The corneal epithelium converges at the peripheral zone (limbus) with the
conjunctival epithelium, forming a continuous sheet with phenotypically distinct regions--
central, limbal, and conjunctival. The epithelial basement membrane (EBM) is important for
corneal functions and cell adhesion, but its regional composition is poorly understood.
Current literature is controversial as to the occurrence of type IV collagen in the cornea. The
aim of this study was to investigate in detail corneal basement membrane (BM) composition …
conjunctival epithelium, forming a continuous sheet with phenotypically distinct regions--
central, limbal, and conjunctival. The epithelial basement membrane (EBM) is important for
corneal functions and cell adhesion, but its regional composition is poorly understood.
Current literature is controversial as to the occurrence of type IV collagen in the cornea. The
aim of this study was to investigate in detail corneal basement membrane (BM) composition …
Background
The corneal epithelium converges at the peripheral zone (limbus) with the conjunctival epithelium, forming a continuous sheet with phenotypically distinct regions--central, limbal, and conjunctival. The epithelial basement membrane (EBM) is important for corneal functions and cell adhesion, but its regional composition is poorly understood. Current literature is controversial as to the occurrence of type IV collagen in the cornea. The aim of this study was to investigate in detail corneal basement membrane (BM) composition and correlate it with the differentiation state of contributing cells.
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