Changes in organization and composition of the extracellular matrix underlying cultured endothelial cells exposed to laminar steady shear stress.
O Thoumine, RM Nerem, PR Girard - Laboratory investigation; a …, 1995 - europepmc.org
O Thoumine, RM Nerem, PR Girard
Laboratory investigation; a journal of technical methods and pathology, 1995•europepmc.orgBackground In blood vessels, the extracellular matrix (ECM) underlying the endothelium
supports endothelial cell (EC) attachment, spreading, migration, and proliferation. The
structure and composition of the ECM may be modulated by hemodynamic shear stress,
which may play a role in the pathogenesis of vascular diseases such as atherosclerosis.
supports endothelial cell (EC) attachment, spreading, migration, and proliferation. The
structure and composition of the ECM may be modulated by hemodynamic shear stress,
which may play a role in the pathogenesis of vascular diseases such as atherosclerosis.
Background
In blood vessels, the extracellular matrix (ECM) underlying the endothelium supports endothelial cell (EC) attachment, spreading, migration, and proliferation. The structure and composition of the ECM may be modulated by hemodynamic shear stress, which may play a role in the pathogenesis of vascular diseases such as atherosclerosis.
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