Thiamine transport by human intestine in vitro
G Rindi, G Ferrari - Experientia, 1977 - Springer
G Rindi, G Ferrari
Experientia, 1977•SpringerSurgical specimens of human gastrointestinal mucosa and muscle were incubated in vitro
with thiaminethiazole-2-14 C. Labelled thiamine uptake was uphill in mucosal tissues and
downhill in muscle. Small intestinal mucosa accumulated labelled thiamine in a
phosphorylated form, while gastric and colonic mucosa, as well as muscular layers of all
gastrointestinal segments studied, did not.
with thiaminethiazole-2-14 C. Labelled thiamine uptake was uphill in mucosal tissues and
downhill in muscle. Small intestinal mucosa accumulated labelled thiamine in a
phosphorylated form, while gastric and colonic mucosa, as well as muscular layers of all
gastrointestinal segments studied, did not.
Summary
Surgical specimens of human gastrointestinal mucosa and muscle were incubated in vitro with thiaminethiazole-2-14C. Labelled thiamine uptake was uphill in mucosal tissues and downhill in muscle. Small intestinal mucosa accumulated labelled thiamine in a phosphorylated form, while gastric and colonic mucosa, as well as muscular layers of all gastrointestinal segments studied, did not.
Springer