Characterization of Cl− HCO3− exchange in cultured bovine pigmented ciliary epithelium
H Helbig, C Korbmacher, D Kühner, S Berweck… - Experimental eye …, 1988 - Elsevier
Many recent data indicate that transport of Cl− across the ciliary epithelium plays an
important role in aqueous humor formation. We used 36 Cl to investigate the pathways for
Cl−-transport in confluent monolayers of cultured bovine pigmented ciliary epithelial cells.
Cl−-uptake mainly occurred via a mechanism with typical characteristics of an anion
exchanger, and could be stimulated by an outwardly directed HCO 3− gradient. One mm
SITS and 1 mm DIDS inhibited Cl−, I− and Br−, by NO 3−, formate and acetate. Inhibition of …
important role in aqueous humor formation. We used 36 Cl to investigate the pathways for
Cl−-transport in confluent monolayers of cultured bovine pigmented ciliary epithelial cells.
Cl−-uptake mainly occurred via a mechanism with typical characteristics of an anion
exchanger, and could be stimulated by an outwardly directed HCO 3− gradient. One mm
SITS and 1 mm DIDS inhibited Cl−, I− and Br−, by NO 3−, formate and acetate. Inhibition of …
