Porcine endogenous retrovirus transmission characteristics of an inbred herd of miniature swine
BA Oldmixon, JC Wood, TA Ericsson… - Journal of …, 2002 - Am Soc Microbiol
BA Oldmixon, JC Wood, TA Ericsson, CA Wilson, ME White-Scharf, G Andersson…
Journal of virology, 2002•Am Soc MicrobiolHere we report the identification of inbred miniature swine that failed to produce human-
tropic replication-competent porcine endogenous retroviruses (HTRC PERVs), using in vitro
coculture assays. When HTRC PERVs were isolated from transmitting animals, all were
recombinant viruses, with the receptor-binding domain of PERV-A combining with PERV-C-
related sequences.
tropic replication-competent porcine endogenous retroviruses (HTRC PERVs), using in vitro
coculture assays. When HTRC PERVs were isolated from transmitting animals, all were
recombinant viruses, with the receptor-binding domain of PERV-A combining with PERV-C-
related sequences.
Abstract
Here we report the identification of inbred miniature swine that failed to produce human-tropic replication-competent porcine endogenous retroviruses (HTRC PERVs), using in vitro coculture assays. When HTRC PERVs were isolated from transmitting animals, all were recombinant viruses, with the receptor-binding domain of PERV-A combining with PERV-C-related sequences.
American Society for Microbiology