Role of interendothelial adhesion molecules in the control of vascular functions

M Aurrand-Lions, C Johnson-Léger, BA Imhof - Vascular pharmacology, 2002 - Elsevier
The function of endothelium is the lining of the vessel wall and the control of vascular
permeability, homeostasis and leukocyte emigration from the blood into the surrounding
tissue. Different adhesion molecules expressed in a coordinated and regulated way control
this function. In this review, we discuss adhesion molecules involved in endothelial junctions
and their involvement in leukocyte transendothelial migration. Passage of the leukocyte
across the endothelium appears to require delocalization of certain vascular adhesion …