Association of long QT syndrome loci and cardiac events among patients treated with β-blockers
ContextData on the efficacy of β-blockers in the 3 most common genetic long QT syndrome
(LQTS) loci are limited. ObjectiveTo describe and assess outcome in a large systematically
genotyped population of β-blocker–treated LQTS patients. Design, Setting, and
PatientsConsecutive LQTS-genotyped patients (n= 335) in Italy treated with β-blockers for
an average of 5 years. Main Outcome MeasuresCardiac events (syncope, ventricular
tachycardia/torsades de pointes, cardiac arrest, and sudden cardiac death) while patients …
(LQTS) loci are limited. ObjectiveTo describe and assess outcome in a large systematically
genotyped population of β-blocker–treated LQTS patients. Design, Setting, and
PatientsConsecutive LQTS-genotyped patients (n= 335) in Italy treated with β-blockers for
an average of 5 years. Main Outcome MeasuresCardiac events (syncope, ventricular
tachycardia/torsades de pointes, cardiac arrest, and sudden cardiac death) while patients …
