[HTML][HTML] Protein kinase Bα/Akt1 regulates placental development and fetal growth
ZZ Yang, O Tschopp, M Hemmings-Mieszczak… - Journal of Biological …, 2003 - ASBMB
Protein kinase Bα (PKBα/Akt1) is implicated in the regulation of metabolism, transcription,
cell survival, angiogenesis, cell migration, growth, and tumorigenesis. Previously, it was
reported that PKBα-deficient mice are small with increased neonatal mortality (Cho, H.,
Thorvaldsen, JL, Chu, Q., Feng, F., and Birnbaum, MJ (2001) J. Biol. Chem. 276, 38349–
38352 and Chen, WS, Xu, PZ, Gottlob, K., Chen, ML, Sokol, K., Shiyanova, T., Roninson, I.,
Wenig, W., Suzuki, R., Tobe, K., Kadowaki, T., and Hay, N.(2001) Genes Dev. 15, 2203 …
cell survival, angiogenesis, cell migration, growth, and tumorigenesis. Previously, it was
reported that PKBα-deficient mice are small with increased neonatal mortality (Cho, H.,
Thorvaldsen, JL, Chu, Q., Feng, F., and Birnbaum, MJ (2001) J. Biol. Chem. 276, 38349–
38352 and Chen, WS, Xu, PZ, Gottlob, K., Chen, ML, Sokol, K., Shiyanova, T., Roninson, I.,
Wenig, W., Suzuki, R., Tobe, K., Kadowaki, T., and Hay, N.(2001) Genes Dev. 15, 2203 …