Obligatory role of lipid mediators in platelet–neutrophil adhesion
S Chlopicki, M Lomnicka, RJ Gryglewski - Thrombosis research, 2003 - Elsevier
Platelet–neutrophil interactions play an important role in thrombotic and inflammatory
responses. Although it is well known that adhesion of platelets to neutrophils requires
interactions of adhesion molecules on platelets such as P-selectin, or GPIIb/IIIa with their
counterparts on neutrophils, little is known on the role of lipid mediators in this response.
Here we studied involvement of thromboxane (TX) A2, platelet activating factor (PAF) and
cysteinyl leukotrienes (cysLTs) in the mechanisms of platelet–neutrophil adhesion that was …
responses. Although it is well known that adhesion of platelets to neutrophils requires
interactions of adhesion molecules on platelets such as P-selectin, or GPIIb/IIIa with their
counterparts on neutrophils, little is known on the role of lipid mediators in this response.
Here we studied involvement of thromboxane (TX) A2, platelet activating factor (PAF) and
cysteinyl leukotrienes (cysLTs) in the mechanisms of platelet–neutrophil adhesion that was …