Genetic variants of the T-cell immunoglobulin mucin 1 but not the T-cell immunoglobulin mucin 3 gene are associated with asthma in an African American population
BACKGROUND: The T-cell immunoglobulin mucin (TIM) proteins and their genetic variants
have been suggested to play a role in regulating allergic diseases. OBJECTIVE: Genetic
association of the sequence variants for TIM-1 and TIM-3 genes with asthma in an African
American population was investigated. METHODS: Both case-control and family-based
association analyses were performed for a total of 7 polymorphisms, including 3 single
nucleotide polymorphism (SNPs) and 1 insertion/deletion polymorphism in the TIM-1 and 3 …
have been suggested to play a role in regulating allergic diseases. OBJECTIVE: Genetic
association of the sequence variants for TIM-1 and TIM-3 genes with asthma in an African
American population was investigated. METHODS: Both case-control and family-based
association analyses were performed for a total of 7 polymorphisms, including 3 single
nucleotide polymorphism (SNPs) and 1 insertion/deletion polymorphism in the TIM-1 and 3 …