Effectiveness and cost of olanzapine and haloperidol in the treatment of schizophrenia: a randomized controlled trial

R Rosenheck, D Perlick, S Bingham, W Liu-Mares… - Jama, 2003 - jamanetwork.com
ContextAlthough olanzapine has been widely adopted as a treatment of choice for
schizophrenia, its long-term effectiveness and costs have not been evaluated in a controlled
trial in comparison with a standard antipsychotic drug. ObjectiveTo evaluate the
effectiveness and cost impact of olanzapine compared with haloperidol in the treatment of
schizophrenia. Design and SettingDouble-blind, randomized controlled trial with
randomization conducted between June 1998 and June 2000 at 17 US Department of …