In vivo recognition and clearance of red blood cells containing phosphatidylserine in their plasma membranes.
AJ Schroit, JW Madsen, Y Tanaka - Journal of Biological Chemistry, 1985 - ASBMB
We have previously investigated the interaction of macrophages with red blood cells (RBC)
displaying phosphatidylserine (PS) in their surface membranes after the transfer of the
fluorescent lipid analog 1-acyl-2-[(N-4-nitrobenzo-2-oxa-1, 3-diazole) aminocaproyl]
phosphatidylserine to the RBC (Tanaka, Y., and Schroit, AJ (1983) J. Biol. Chem. 258,
11335-11343). This derivative, which is rapidly transferred to the RBC at 37 degrees C,
results in the efficient binding and phagocytosis of the RBC by autologous macrophages. In …
displaying phosphatidylserine (PS) in their surface membranes after the transfer of the
fluorescent lipid analog 1-acyl-2-[(N-4-nitrobenzo-2-oxa-1, 3-diazole) aminocaproyl]
phosphatidylserine to the RBC (Tanaka, Y., and Schroit, AJ (1983) J. Biol. Chem. 258,
11335-11343). This derivative, which is rapidly transferred to the RBC at 37 degrees C,
results in the efficient binding and phagocytosis of the RBC by autologous macrophages. In …
