Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock

Y Sakr, MJ Dubois, D De Backer, J Creteur… - Critical care …, 2004 - journals.lww.com
Objective: To characterize the time course of microcirculatory alterations and their relation to
outcome in patients with septic shock. Design: Prospective, observational study. Setting:
Thirty-one-bed, medico-surgical intensive care unit in a university hospital. Patients: Forty-
nine patients with septic shock. Interventions: The sublingual microcirculation was
investigated with an orthogonal polarization spectral imaging device on the day of onset of
septic shock (baseline) and each day until resolution of shock. Measurements and Main …