Cryptococcus neoformans var. neoformans(Serotype D) Strains Are More Susceptible to Heat than C. neoformans var. grubii (Serotype A) Strains
LR Martinez, J Garcia-Rivera… - Journal of Clinical …, 2001 - Am Soc Microbiol
LR Martinez, J Garcia-Rivera, A Casadevall
Journal of Clinical Microbiology, 2001•Am Soc MicrobiolCryptococcus neoformans var. neoformans (serotype D) and C. neoformans var. grubii
(serotype A) differ in geographic prevalence and dermatotropism, with C. neoformans var.
neoformans strains being more prevalent among isolates from temperate countries as well
as from skin infections. Analysis of 19 strains from each serotype revealed wide variation in
thermal susceptibility, with C. neoformans var. neoformans strains being more susceptible,
on average, to heat killing. The results suggest a consistent explanation for the geographic …
(serotype A) differ in geographic prevalence and dermatotropism, with C. neoformans var.
neoformans strains being more prevalent among isolates from temperate countries as well
as from skin infections. Analysis of 19 strains from each serotype revealed wide variation in
thermal susceptibility, with C. neoformans var. neoformans strains being more susceptible,
on average, to heat killing. The results suggest a consistent explanation for the geographic …
Abstract
Cryptococcus neoformans var. neoformans(serotype D) and C. neoformans var. grubii(serotype A) differ in geographic prevalence and dermatotropism, withC. neoformans var. neoformans strains being more prevalent among isolates from temperate countries as well as from skin infections. Analysis of 19 strains from each serotype revealed wide variation in thermal susceptibility, with C. neoformans var. neoformans strains being more susceptible, on average, to heat killing. The results suggest a consistent explanation for the geographic differences between serotype A and D strains and for the dermatotropism of serotype D strains.
American Society for Microbiology