Macrophages and monocytes are adherent phagocytic cells which play an important role in
host defence against the yeast-like fungus Cryptococcus neoformans. Before, phagocytosis
by adherent phagocytes could only be measured by means of microscopy or by a
radioactive assay, which both have obvious disadvantages. We have developed a new,
rapid and objective method to measure phagocytosis of C. neoformans by adherent
phagocytes (eg alveolar macrophages) using a fluorescence multi-well plate reader. This …