Augmentation therapy reduces frequency of lung infections in antitrypsin deficiency: a new hypothesis with supporting data
J Lieberman - Chest, 2000 - Elsevier
Study objectives To propose an hypothesis thatantiprotease augmentation therapy reduces
the incidence of lunginfections in α 1-antitrypsin (AAT)-deficient patients, and to present
supporting data. Design Theproposed concept is based on a survey taken via the Internet
ofpatients receiving augmentation therapy for 1 to 10 years compared tosimilar patients not
receiving such therapy. Setting A questionnaire was submitted to patients with a ZZ
phenotype for AATdeficiency to determine whether those receiving antitrypsinaugmentation …
the incidence of lunginfections in α 1-antitrypsin (AAT)-deficient patients, and to present
supporting data. Design Theproposed concept is based on a survey taken via the Internet
ofpatients receiving augmentation therapy for 1 to 10 years compared tosimilar patients not
receiving such therapy. Setting A questionnaire was submitted to patients with a ZZ
phenotype for AATdeficiency to determine whether those receiving antitrypsinaugmentation …