[HTML][HTML] Tracing the retrograde route in protein trafficking
L Johannes, V Popoff - Cell, 2008 - cell.com
L Johannes, V Popoff
Cell, 2008•cell.comRetrograde transport, in which proteins and lipids are shuttled between endosomes and
biosynthetic/secretory compartments such as the Golgi apparatus, is crucial for a diverse
range of cellular functions. Mechanistic studies that explore the molecular machinery
involved in this retrograde trafficking route are shedding light on the functions of transport
proteins and are providing fresh insights into possible new therapeutic directions.
biosynthetic/secretory compartments such as the Golgi apparatus, is crucial for a diverse
range of cellular functions. Mechanistic studies that explore the molecular machinery
involved in this retrograde trafficking route are shedding light on the functions of transport
proteins and are providing fresh insights into possible new therapeutic directions.
Retrograde transport, in which proteins and lipids are shuttled between endosomes and biosynthetic/secretory compartments such as the Golgi apparatus, is crucial for a diverse range of cellular functions. Mechanistic studies that explore the molecular machinery involved in this retrograde trafficking route are shedding light on the functions of transport proteins and are providing fresh insights into possible new therapeutic directions.
cell.com