Infection of mice with murine cytomegalovirus (MCMV) is an established model for studying
human cytomegalovirus (HCMV) infection. Similarly to HCMV infection, pathological
changes and disease manifestations during MCMV infection are mainly dependent on the
immune status of the mouse host. This review focuses mainly on the pathogenesis of MCMV
infection in immunocompetent and immunodeficient and/or immature mice and discusses
the principles of immunosurveillance of infection and the mechanisms by which this virus …