[HTML][HTML] Phase III, randomized, open-label study of daily imatinib mesylate 400 mg versus 800 mg in patients with newly diagnosed, previously untreated chronic …

JE Cortes, M Baccarani, F Guilhot… - Journal of Clinical …, 2010 - ncbi.nlm.nih.gov
JE Cortes, M Baccarani, F Guilhot, BJ Druker, S Branford, DW Kim, F Pane, R Pasquini…
Journal of Clinical Oncology, 2010ncbi.nlm.nih.gov
Phase III, Randomized, Open-Label Study of Daily Imatinib Mesylate 400 mg Versus 800 mg in
Patients With Newly Diagnosed, Previously Untreated Chronic Myeloid Leukemia in Chronic
Phase Using Molecular End Points: Tyrosine Kinase Inhibitor Optimization and Selectivity
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Abstract
Purpose
To evaluate the safety and efficacy of initial treatment with imatinib mesylate 800 mg/d (400 mg twice daily) versus 400 mg/d in patients with newly diagnosed chronic myeloid leukemia in chronic phase.
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