Pregnancy-associated malaria and the prospects for syndrome-specific antimalaria vaccines

JD Smith, KW Deitsch - The Journal of experimental medicine, 2004 - rupress.org
JD Smith, KW Deitsch
The Journal of experimental medicine, 2004rupress.org
Aided by the Plasmodium falciparum genome project, recent discoveries regarding the
molecular basis of malaria pathogenesis have led to a better understanding of the
interactions between host and parasite. Although vaccines that prevent infection by malaria
parasites remain only hopes for the future, there are now more immediate prospects for
vaccines that protect against specific disease syndromes. Here, we discuss the latest
advances in the development of a vaccine that specifically targets pregnancy-associated …
Aided by the Plasmodium falciparum genome project, recent discoveries regarding the molecular basis of malaria pathogenesis have led to a better understanding of the interactions between host and parasite. Although vaccines that prevent infection by malaria parasites remain only hopes for the future, there are now more immediate prospects for vaccines that protect against specific disease syndromes. Here, we discuss the latest advances in the development of a vaccine that specifically targets pregnancy-associated malaria (PAM).
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