Clinical radiation sensitivity with DNA repair disorders: an overview
JM Pollard, RA Gatti - International Journal of Radiation Oncology* Biology …, 2009 - Elsevier
Adverse reactions to radiotherapy represent a confounding phenomenon in radiation
oncology. These reactions are rare, and many have been associated with individuals with
DNA repair disorders such as ataxia-telangiectasia and Nijmegen Breakage syndrome. A
paucity of published data is available detailing such circumstances. This overview describes
four exemplary situations, a comprehensive list of 32 additional cases, and some insights
gleaned from this overall experience. Fanconi anemia was associated with more than one …
oncology. These reactions are rare, and many have been associated with individuals with
DNA repair disorders such as ataxia-telangiectasia and Nijmegen Breakage syndrome. A
paucity of published data is available detailing such circumstances. This overview describes
four exemplary situations, a comprehensive list of 32 additional cases, and some insights
gleaned from this overall experience. Fanconi anemia was associated with more than one …
