Microvascular changes in small airways predispose to obliterative bronchiolitis after lung transplantation

H Luckraz, M Goddard, K McNeil, C Atkinson… - The Journal of heart and …, 2004 - Elsevier
BACKGROUND: There is strong evidence that obliterative bronchiolitis (OB) in lung
transplant recipients is related to acute rejection as graded by parenchymal perivascular
infiltrates. OB (chronic rejection) is a small airways, rather than a parenchymal, scarring
process. Moreover, there has been no study of the microcirculation in the small airways in
lung transplantation. This study assesses the microvasculature around small airways (SA) in
post-mortem lung allograft specimens. METHODS: The microvasculature of SA (n= 19) from …