Several psychiatric disorders increase the risk of cardiovascular disease, including
posttraumatic stress disorder and major depression. While the precise mechanism for this
association has not yet been established, it has been shown that certain disorders promote
an unfavorable lipid profile. To study the interaction of stress and lipid dysregulation, we
utilized chronic social defeat stress (CSDS), a mouse model of chronic stress with features of
posttraumatic stress disorder and major depression. Following exposure to CSDS, mice …