Conjugative Transfer by the Virulence System of Agrobacterium tumefaciens

A Beijersbergen, AD Dulk-Ras, RA Schilperoort… - Science, 1992 - science.org
A Beijersbergen, AD Dulk-Ras, RA Schilperoort, PJJ Hooykaas
Science, 1992science.org
Agrobacterium tumefaciens transfers part of its Ti plasmid, the transferred DNA (T-DNA), to
plant cells during tumor induction. Expression of this T-DNA in plant cells results in their
transformation into tumor cells. There are similarities between the process of T-DNA transfer
to plants and the process of bacterial conjugation. Here, the T-DNA transfer machinery
mediated conjugation between bacteria. Thus, products of the Vir region of the Ti plasmid of
Agrobacterium tumefaciens, normally involved in transfer of DNA from bacteria to plants, can …
Agrobacterium tumefaciens transfers part of its Ti plasmid, the transferred DNA (T-DNA), to plant cells during tumor induction. Expression of this T-DNA in plant cells results in their transformation into tumor cells. There are similarities between the process of T-DNA transfer to plants and the process of bacterial conjugation. Here, the T-DNA transfer machinery mediated conjugation between bacteria. Thus, products of the Vir region of the Ti plasmid of Agrobacterium tumefaciens, normally involved in transfer of DNA from bacteria to plants, can direct the conjugative transfer of an IncQ plasmid between agrobacteria.
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