Effect of prone positioning on clinical outcomes in children with acute lung injury: a randomized controlled trial

MAQ Curley, PL Hibberd, LD Fineman, D Wypij… - Jama, 2005 - jamanetwork.com
ContextIn uncontrolled clinical studies, prone positioning appeared to be safe and to
improve oxygenation in pediatric patients with acute lung injury. However, the effect of prone
positioning on clinical outcomes in children is not known. ObjectiveTo test the hypothesis
that at the end of 28 days infants and children with acute lung injury treated with prone
positioning would have more ventilator-free days than those treated with supine positioning.
Design, Setting, and PatientsMulticenter, randomized, controlled clinical trial conducted from …