Atherosclerosis involves the formation of inflammatory arterial lesions and is one of the most
common causes of death globally. It has been evident for more than 20 years that adaptive
immunity and T cells in particular regulate the magnitude of the atherogenic pro-
inflammatory response. T cells also influence the stability of the atherosclerotic lesion and
thus the propensity for thrombus formation and the clinical outcome of disease. This review
summarizes our current understanding of T cells in atherogenesis, including which antigens …