[PDF][PDF] Lysosomal enhancement: a CLEAR answer to cellular degradative needs
M Sardiello, A Ballabio - Cell cycle, 2009 - Taylor & Francis
Cell cycle, 2009•Taylor & Francis
Lysosomal enhancement: A CLEAR answer to cellular degradative needs Page 1 www.landesbioscience.com
Cell Cycle 4021 Cell Cycle 8:24, 4021-4022; December 15, 2009; © 2009 Landes Bioscience
CeLL CyCLe Features Features improves cellular degradative capabilities, as demonstrated
by the faster breakdown of glycosaminoglycans, a process that needs the concerted action
of several lysosomal hydrolases.Interestingly, TFEB also regulates key autophagy switches,
which indicates that the CLEAR network extends beyond the lysosomal complement to favor …
Cell Cycle 4021 Cell Cycle 8:24, 4021-4022; December 15, 2009; © 2009 Landes Bioscience
CeLL CyCLe Features Features improves cellular degradative capabilities, as demonstrated
by the faster breakdown of glycosaminoglycans, a process that needs the concerted action
of several lysosomal hydrolases.Interestingly, TFEB also regulates key autophagy switches,
which indicates that the CLEAR network extends beyond the lysosomal complement to favor …
Comment on: Sardiello M, et al. A gene network regulating lysosomal biogenesis and function. Science 2009; 325:473-7.
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