IMF-κB and rel: Participants in a multiform transcriptional regulatory system
M Grilli, JJS Chiu, MJ Lenardo - International review of cytology, 1993 - Elsevier
Publisher Summary This chapter highlights NF-кB/Rel protein complex. Associations of the
binding and regulatory subunits of NF-кB operate at the center of a variety of different signal
pathways. NF-кB can process and integrate instructions that come from the extracellular
environment and detect intracellular events originating in either the cytoplasm or the
nucleus. NF-кB then transmits this information with astonishing rapidity to the transcriptional
machinery by directly binding to a range of different DNA sequences in gene control regions …
binding and regulatory subunits of NF-кB operate at the center of a variety of different signal
pathways. NF-кB can process and integrate instructions that come from the extracellular
environment and detect intracellular events originating in either the cytoplasm or the
nucleus. NF-кB then transmits this information with astonishing rapidity to the transcriptional
machinery by directly binding to a range of different DNA sequences in gene control regions …