[HTML][HTML] ESDN, a novel neuropilin-like membrane protein cloned from vascular cells with the longest secretory signal sequence among eukaryotes, is up-regulated …
K Kobuke, Y Furukawa, M Sugai, K Tanigaki… - Journal of Biological …, 2001 - ASBMB
A novel cDNA has been isolated from primary culture of human coronary arterial cells by a
signal sequence trap method, and designated ESDN (endothelial andsmooth muscle cell-
derivedneuropilin-like molecule). ESDN is a type-I transmembrane protein with the longest
cleavable secretory signal sequence among eukaryotes. ESDN contains a CUB domain and
a coagulation factor V/VIII homology domain, which reminds us of the structure of
neuropilins. ESDN also harbors an LCCL domain, which is shared by Limulus factor C and …
signal sequence trap method, and designated ESDN (endothelial andsmooth muscle cell-
derivedneuropilin-like molecule). ESDN is a type-I transmembrane protein with the longest
cleavable secretory signal sequence among eukaryotes. ESDN contains a CUB domain and
a coagulation factor V/VIII homology domain, which reminds us of the structure of
neuropilins. ESDN also harbors an LCCL domain, which is shared by Limulus factor C and …