[HTML][HTML] Heterogenous turnover of sperm and seminal vesicle proteins in the mouse revealed by dynamic metabolic labeling

AJ Claydon, SA Ramm, A Pennington, JL Hurst… - Molecular & Cellular …, 2012 - ASBMB
Plasticity in ejaculate composition is predicted as an adaptive response to the evolutionary
selective pressure of sperm competition. However, to respond rapidly to local competitive
conditions requires dynamic modulation in the production of functionally relevant ejaculate
proteins. Here we combine metabolic labeling of proteins with proteomics to explore the
opportunity for such modulation within mammalian ejaculates. We assessed the rate at
which proteins are synthesized and incorporated in the seminal vesicles of male house mice …