Expression of complement components differs between kidney allografts from living and deceased donors

M Naesens, L Li, L Ying, P Sansanwal… - Journal of the …, 2009 - journals.lww.com
A disparity remains between graft survival of renal allografts from deceased donors and from
living donors. A better understanding of the molecular mechanisms that underlie this
disparity may allow the development of targeted therapies to enhance graft survival. Here,
we used microarrays to examine whole genome expression profiles using tissue from 53
human renal allograft protocol biopsies obtained both at implantation and after
transplantation. The gene expression profiles of living-donor kidneys and pristine deceased …