Low-grade proteinuria and microalbuminuria in renal transplantation
JM Halimi - Transplantation, 2013 - journals.lww.com
Transplantation, 2013•journals.lww.com
Nephrotic-range proteinuria has been known for years to be associated with poor renal
outcome. Newer evidence indicates that early (1–3 months after transplantation) low-grade
proteinuria and microalbuminuria (1) provide information on the graft in terms of donor
characteristics and ischemia/reperfusion injury,(2) may occur before the development of
donor-specific antibodies,(3) predict the development of diabetes and cardiovascular
events, and (4) are associated with reduced long-term graft and patient survivals.
outcome. Newer evidence indicates that early (1–3 months after transplantation) low-grade
proteinuria and microalbuminuria (1) provide information on the graft in terms of donor
characteristics and ischemia/reperfusion injury,(2) may occur before the development of
donor-specific antibodies,(3) predict the development of diabetes and cardiovascular
events, and (4) are associated with reduced long-term graft and patient survivals.
Abstract
Nephrotic-range proteinuria has been known for years to be associated with poor renal outcome. Newer evidence indicates that early (1–3 months after transplantation) low-grade proteinuria and microalbuminuria (1) provide information on the graft in terms of donor characteristics and ischemia/reperfusion injury,(2) may occur before the development of donor-specific antibodies,(3) predict the development of diabetes and cardiovascular events, and (4) are associated with reduced long-term graft and patient survivals.
Lippincott Williams & Wilkins