Congenital deficiency of factor XIII: Report of a family from Newfoundland with associated mild deficiency of factor XII
M Hanna - Pediatrics, 1970 - publications.aap.org
In a family with 14 children severe deficiency of factor XIII was found in three living members
who suffered from moderate to severe bleeding manifestations. A fourth child died with
intracranial hemorrhage. In addition to the above deficiency, two of the three propositi and
two siblings were mildly deficient in factor XII. The bleeding manifestations of these cases
are solely due to factor XIII deficiency; siblings with factor XII deficiency alone were
asymptomatic. Both factor deficiencies here seem to be separately inherited. The most …
who suffered from moderate to severe bleeding manifestations. A fourth child died with
intracranial hemorrhage. In addition to the above deficiency, two of the three propositi and
two siblings were mildly deficient in factor XII. The bleeding manifestations of these cases
are solely due to factor XIII deficiency; siblings with factor XII deficiency alone were
asymptomatic. Both factor deficiencies here seem to be separately inherited. The most …