New developments in radiation therapy for head and neck cancer: intensity-modulated radiation therapy and hypoxia targeting

NY Lee, QT Le - Seminars in oncology, 2008 - Elsevier
Intensity-modulated radiation therapy (IMRT) has revolutionized radiation treatment for head
and neck cancers (HNCs). When compared to the traditional techniques, IMRT has the
unique ability to minimize the dose delivered to normal tissues without compromising tumor
coverage. As a result, side effects from high-dose radiation have decreased and patient
quality of life has improved. In addition to toxicity reduction, excellent clinical outcomes have
been reported for IMRT. The first part of this review will focus on clinical results of IMRT for …