Effects of perceived treatment on quality of life and medical outcomesin a double-blind placebo surgery trial
C McRae, E Cherin, TG Yamazaki… - Archives of general …, 2004 - jamanetwork.com
Context This study was part of a large double-blind sham surgery–controlled trial designed
to determine the effectiveness of transplantation of human embryonic dopamine neurons
into the brains of persons with advanced Parkinson's disease. This portion of the study
investigated the quality of life (QOL) of participants during the 1 year of double-blind follow-
up. Objectives To determine whether QOL improved more in the transplant group than in the
sham surgery group and to investigate outcomes at 1 year based on perceived treatment …
to determine the effectiveness of transplantation of human embryonic dopamine neurons
into the brains of persons with advanced Parkinson's disease. This portion of the study
investigated the quality of life (QOL) of participants during the 1 year of double-blind follow-
up. Objectives To determine whether QOL improved more in the transplant group than in the
sham surgery group and to investigate outcomes at 1 year based on perceived treatment …