[HTML][HTML] Notch signaling pathway and Cdx2 expression in the development of Barrett's esophagus
Y Tamagawa, N Ishimura, G Uno, T Yuki… - Laboratory …, 2012 - Elsevier
Cdx2 expression in esophageal stem cells induced by reflux bile acids may be an important
factor for development of Barrett's esophagus, whereas Notch signaling is a molecular
signaling pathway that plays an important role in the determination of cell differentiation.
ATOH1 (a factor associated with Notch signaling) plays an important role in differentiation of
stem cells into goblet cells. However, the relationship between the Notch signaling pathway
and Cdx2 expression in the development of Barrett's esophagus has not been explored. The …
factor for development of Barrett's esophagus, whereas Notch signaling is a molecular
signaling pathway that plays an important role in the determination of cell differentiation.
ATOH1 (a factor associated with Notch signaling) plays an important role in differentiation of
stem cells into goblet cells. However, the relationship between the Notch signaling pathway
and Cdx2 expression in the development of Barrett's esophagus has not been explored. The …