[HTML][HTML] Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography
CM Petersen, MS Nielsen, A Nykjær… - Journal of Biological …, 1997 - ASBMB
Receptor-associated protein (RAP) is an endoplasmic reticulum/Golgi protein involved in the
processing of receptors of the low density lipoprotein receptor family. A∼ 95-kDa membrane
glycoprotein, designated gp95/sortilin, was purified from human brain extracts by RAP
affinity chromatography and cloned in a human cDNA library. The gene maps to
chromosome 1p and encodes an 833-amino acid type I receptor containing an N-terminal
furin cleavage site immediately preceding the N terminus determined in the purified protein …
processing of receptors of the low density lipoprotein receptor family. A∼ 95-kDa membrane
glycoprotein, designated gp95/sortilin, was purified from human brain extracts by RAP
affinity chromatography and cloned in a human cDNA library. The gene maps to
chromosome 1p and encodes an 833-amino acid type I receptor containing an N-terminal
furin cleavage site immediately preceding the N terminus determined in the purified protein …