A review of pathophysiology and management of fetuses and neonates with meconium ileus for the pediatric surgeon
BE Carlyle, DS Borowitz, PL Glick - Journal of pediatric surgery, 2012 - Elsevier
PURPOSE: Meconium ileus (MI) is the earliest clinical manifestation of cystic fibrosis (CF),
occurring in up to 20% of patients with CF. Our aim was to review and integrate current
knowledge about the diagnosis and management of fetuses and neonates with MI that may
aid the pediatric surgeon in caring for these patients. METHODS: We identified areas of
interest including pathophysiology, prenatal diagnosis, nonoperative and operative
management, postoperative management, and prognosis. We performed a Medline search …
occurring in up to 20% of patients with CF. Our aim was to review and integrate current
knowledge about the diagnosis and management of fetuses and neonates with MI that may
aid the pediatric surgeon in caring for these patients. METHODS: We identified areas of
interest including pathophysiology, prenatal diagnosis, nonoperative and operative
management, postoperative management, and prognosis. We performed a Medline search …