[HTML][HTML] Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes
JM Escola, MJ Kleijmeer, W Stoorvogel… - Journal of Biological …, 1998 - ASBMB
Association of major histocompatibility complex (MHC) class II molecules with peptides
occurs in a series of endocytic vacuoles, termed MHC class II-enriched compartments
(MIICs). Morphological criteria have defined several types of MIICs, including multivesicular
MIICs, which are composed of 50–60-nm vesicles surrounded by a limiting membrane.
Multivesicular MIICs can fuse with the plasma membrane, thereby releasing their internal
vesicles into the extracellular space. The externalized vesicles, termed exosomes, carry …
occurs in a series of endocytic vacuoles, termed MHC class II-enriched compartments
(MIICs). Morphological criteria have defined several types of MIICs, including multivesicular
MIICs, which are composed of 50–60-nm vesicles surrounded by a limiting membrane.
Multivesicular MIICs can fuse with the plasma membrane, thereby releasing their internal
vesicles into the extracellular space. The externalized vesicles, termed exosomes, carry …