[HTML][HTML] Differential stimulation of monocytic cells results in distinct populations of microparticles
M Bernimoulin, EK Waters, M Foy, BM Steele… - Journal of Thrombosis …, 2009 - Elsevier
Background: Microparticles (MPs), small vesicles shed from stimulated cells, permit cross-
talk between cells within a particular environment. Their composition is thought to reflect
their cell of origin, and differs according to whether they are produced by stimulation or by
apoptosis. Whether MP properties vary according to stimulus is not yet known. Methods: We
studied the characteristics of MPs produced from monocytic THP-1 cells upon stimulation
with lipopolysaccharide or a soluble P-selectin chimera, using proteomics, flow cytometry …
talk between cells within a particular environment. Their composition is thought to reflect
their cell of origin, and differs according to whether they are produced by stimulation or by
apoptosis. Whether MP properties vary according to stimulus is not yet known. Methods: We
studied the characteristics of MPs produced from monocytic THP-1 cells upon stimulation
with lipopolysaccharide or a soluble P-selectin chimera, using proteomics, flow cytometry …