The previous characterization of an abundant population of non-adrenergic imidazoline-I 2
binding sites in adipocytes and the recent demonstration of the interplay between these
binding sites and amine oxidases led us to analyze the amine oxidase activity in
membranes from isolated rat adipocytes. Adipocyte membranes had substantial levels of
semicarbazide-sensitive amine oxidase (SSAO). SSAO activity and immunoreactive SSAO
protein were maximal in plasma membranes, and they were also detectable in intracellular …