What is the value of a food and drug administration investigational new drug application for fecal microbiota transplantation to treat Clostridium difficile Infection?
GA Hecht, MJ Blaser, J Gordon, LM Kaplan… - Clinical …, 2014 - cghjournal.org
Growing evidence suggests that numerous aspects of normal human physiology and
physiological variation, disease risk, and disease pathogenesis may be attributable to the
tens of trillions of microbes that inhabit our gastrointestinal tracts. These microbes are
collectively referred to as the gut microbiota. The number of unique genes in the adult gut
microbial community (microbiome) is 150-fold greater than the number of genes in our
Homo sapiens genome. Although most studies to date have focused on the bacterial …
physiological variation, disease risk, and disease pathogenesis may be attributable to the
tens of trillions of microbes that inhabit our gastrointestinal tracts. These microbes are
collectively referred to as the gut microbiota. The number of unique genes in the adult gut
microbial community (microbiome) is 150-fold greater than the number of genes in our
Homo sapiens genome. Although most studies to date have focused on the bacterial …