The validity of predicted T-cell epitopes
Trends in biotechnology, 2006•cell.com
High-performing MHC class I binding predictions have been available for more than a
decade; however, their value in terms of actual epitope finding has only now been estimated
in a large-scale investigation undertaken by the group of Sette. This work underlines the
importance of bioinformatics as a resource-saving tool in the field of epitope discovery. In
addition, the data can be used to benchmark the performance of other new or existing CTL
epitope-prediction tools.
decade; however, their value in terms of actual epitope finding has only now been estimated
in a large-scale investigation undertaken by the group of Sette. This work underlines the
importance of bioinformatics as a resource-saving tool in the field of epitope discovery. In
addition, the data can be used to benchmark the performance of other new or existing CTL
epitope-prediction tools.
High-performing MHC class I binding predictions have been available for more than a decade; however, their value in terms of actual epitope finding has only now been estimated in a large-scale investigation undertaken by the group of Sette. This work underlines the importance of bioinformatics as a resource-saving tool in the field of epitope discovery. In addition, the data can be used to benchmark the performance of other new or existing CTL epitope-prediction tools.
cell.com