The NOD mouse model of type 1 diabetes: as good as it gets?
MA Atkinson, EH Leiter - Nature medicine, 1999 - nature.com
MA Atkinson, EH Leiter
Nature medicine, 1999•nature.comOf the two well-known rodent models of human type 1 diabetes (the non-obese diabetic
mouse and the BioBreeding rat) the mouse has become the model of choice. Here the
authors re-examine the value of this mouse model as a tool for understanding human
diabetes and for testing potential therapies, reviewing both strengths and weaknesses.
mouse and the BioBreeding rat) the mouse has become the model of choice. Here the
authors re-examine the value of this mouse model as a tool for understanding human
diabetes and for testing potential therapies, reviewing both strengths and weaknesses.
Abstract
Of the two well-known rodent models of human type 1 diabetes (the non-obese diabetic mouse and the BioBreeding rat) the mouse has become the model of choice. Here the authors re-examine the value of this mouse model as a tool for understanding human diabetes and for testing potential therapies, reviewing both strengths and weaknesses.
nature.com