Cytomegalovirus reactivation in critically ill immunocompetent patients

AP Limaye, KA Kirby, GD Rubenfeld, WM Leisenring… - Jama, 2008 - jamanetwork.com
Context Cytomegalovirus (CMV) infection is associated with adverse clinical outcomes in
immunosuppressed persons, but the incidence and association of CMV reactivation with
adverse outcomes in critically ill persons lacking evidence of immunosuppression have not
been well defined. Objective To determine the association of CMV reactivation with intensive
care unit (ICU) and hospital length of stay in critically ill immunocompetent persons. Design,
Setting, and Participants We prospectively assessed CMV plasma DNAemia by thrice …