A pain in the NEC: research challenges and opportunities

GE Besner - Journal of Pediatric Surgery, 2015 - Elsevier
This lecture will describe how the properties of heparin-binding EFG-like growth factor (HB-
EGF) can be utilized to protect the intestines from necrotizing enterocolitis (NEC), to
augment the effects of stem cells in the treatment of NEC, and to improve the production of
tissue-engineered intestine. It will also explore the role of the enteric nervous system in the
development of NEC.