[HTML][HTML] Induction of CX3CL1 expression in astrocytes and CX3CR1 in microglia in the spinal cord of a rat model of neuropathic pain
JA Lindia, E McGowan, N Jochnowitz, C Abbadie - The Journal of Pain, 2005 - Elsevier
Previous studies have shown that chemokines might play a role in the pathology of chronic
pain. The purpose of this study was to provide an immunohistochemical description of the
distribution of CX3CL1 (fractalkine) and its receptor CX3CR1 in the rat spinal cord in a
model of inflammatory pain induced by unilateral intraplantar complete Freund's adjuvant
(CFA) and in a model of neuropathic pain induced by L5 spinal nerve ligation (modified
Chung model or mSNL). In naïve rats, CX3CL1 is found in the cytoplasm of neurons as …
pain. The purpose of this study was to provide an immunohistochemical description of the
distribution of CX3CL1 (fractalkine) and its receptor CX3CR1 in the rat spinal cord in a
model of inflammatory pain induced by unilateral intraplantar complete Freund's adjuvant
(CFA) and in a model of neuropathic pain induced by L5 spinal nerve ligation (modified
Chung model or mSNL). In naïve rats, CX3CL1 is found in the cytoplasm of neurons as …