The jimpy mouse
O Robain - Acta Zoologica et Pathologica Antverpiensia, 1977 - europepmc.org
O Robain
Acta Zoologica et Pathologica Antverpiensia, 1977•europepmc.orgUltrastructural study of the Jimpy mice shows lack of myelin in the central nervous system:
low density of glial cells, defect of maturation of oligodendrocytes and deficiency in axonal
growth. The lack of myelin is more proeminent in late myelinating structures: corpus
callosum and corticospinal fasciculus. Failure in myelin is rather the consequence of an
early interruption of myelination as that of demyelination (a destruction of the sheats).
low density of glial cells, defect of maturation of oligodendrocytes and deficiency in axonal
growth. The lack of myelin is more proeminent in late myelinating structures: corpus
callosum and corticospinal fasciculus. Failure in myelin is rather the consequence of an
early interruption of myelination as that of demyelination (a destruction of the sheats).
Ultrastructural study of the Jimpy mice shows lack of myelin in the central nervous system: low density of glial cells, defect of maturation of oligodendrocytes and deficiency in axonal growth. The lack of myelin is more proeminent in late myelinating structures: corpus callosum and corticospinal fasciculus. Failure in myelin is rather the consequence of an early interruption of myelination as that of demyelination (a destruction of the sheats).
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